The relationship between bone mineral density and arterial stiffness in women

Diagn Interv Radiol. 2012 Sep-Oct;18(5):441-5. doi: 10.4261/1305-3825.DIR.5330-11.1. Epub 2012 Mar 20.

Abstract

Purpose: The aim of this study was to investigate the correlation between bone mineral density (BMD) and arterial stiffness as a preclinical atherosclerosis criterion.

Materials and methods: Carotid and femoral artery Doppler ultrasonography and arterial stiffness measurements were performed on 113 female patients referred for BMD measurements.

Results: The cross-sectional compliance and cross-sectional distensibility of the carotid artery were positively correlated with the BMD of the Ward's triangle, the femoral neck, and the lower femoral neck; and the Ward's triangle, respectively. A negative correlation was found between the intima-media thickness of the femoral artery and the femoral elastic modulus with the BMD of L1, L12, L13, and L23; and the BMD of L1, L3, L13, L24, L34, the femoral neck, the lower femoral neck, and Ward's triangle, respectively. The cross-sectional compliance and cross-sectional distensibility of the femoral artery were positively correlated with the BMD of the femoral neck, upper femoral neck, lower femoral neck, Ward's triangle; and the BMD of the total femur and Ward's triangle, respectively.

Conclusion: The arterial stiffness measurements in women are correlated with BMD, regardless of age and other demographic factors.

Publication types

  • Comparative Study

MeSH terms

  • Absorptiometry, Photon / methods
  • Adult
  • Age Distribution
  • Aged
  • Anthropometry
  • Atherosclerosis / diagnostic imaging*
  • Atherosclerosis / epidemiology
  • Atherosclerosis / physiopathology
  • Bone Density / physiology*
  • Cardiovascular Diseases / diagnostic imaging
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / physiopathology
  • Carotid Arteries / diagnostic imaging
  • Carotid Intima-Media Thickness
  • Cross-Sectional Studies
  • Female
  • Femoral Artery / diagnostic imaging
  • Follow-Up Studies
  • Humans
  • Incidence
  • Middle Aged
  • Osteoporosis / diagnostic imaging
  • Osteoporosis / epidemiology*
  • Osteoporosis / physiopathology
  • Risk Assessment
  • Sensitivity and Specificity
  • Ultrasonography, Doppler / methods
  • Vascular Stiffness / physiology*