Abstract
This report describes the first detection of an equine herpesvirus 1 (EHV-1) neuropathogenic variant (G2254/D752) in Brazil from a case of fatal equine herpesvirus myeloencephalopathy (EHM) in a mare. The results of nucleotide sequencing of the EHV-1 ORF30 gene showed that two other Brazilian EHV-1 isolates from EHM cases are representatives of the non-neuropathogenic variant (A2254/N752), suggesting that other unidentified factors are probably also involved in the neuropathogenicity of EHV-1 in horses. These findings will contribute to the epidemiological knowledge of EHV-1 infection in Brazil.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Brain / pathology
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Brazil / epidemiology
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Encephalitis, Viral / epidemiology
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Encephalitis, Viral / veterinary*
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Encephalitis, Viral / virology
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Euthanasia, Animal
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Fatal Outcome
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Female
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Herpesviridae Infections / epidemiology
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Herpesviridae Infections / veterinary*
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Herpesviridae Infections / virology
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Herpesvirus 1, Equid / genetics
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Herpesvirus 1, Equid / isolation & purification*
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Herpesvirus 1, Equid / pathogenicity
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Horse Diseases / epidemiology*
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Horse Diseases / pathology
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Horse Diseases / virology
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Horses
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Myelitis / epidemiology
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Myelitis / veterinary*
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Myelitis / virology
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Spinal Cord / pathology