Characterization of the novel HLA-C*07:195 allele in an Italian hematopoietic stem cell volunteer donor, detected by sequence-based typing

M Testi; M Battarra; M Troiano; R Condello; M Andreani

doi:10.1111/j.1399-0039.2012.01866.x

Characterization of the novel HLA-C*07:195 allele in an Italian hematopoietic stem cell volunteer donor, detected by sequence-based typing

Tissue Antigens. 2012 Jul;80(1):67-8. doi: 10.1111/j.1399-0039.2012.01866.x. Epub 2012 Mar 22.

Authors

M Testi¹, M Battarra, M Troiano, R Condello, M Andreani

Affiliation

¹ Laboratory of Immunogenetics and Transplant Biology, IME Foundation at Polyclinic of Tor Vergata, Rome, Italy. [email protected]

PMID: 22443801
DOI: 10.1111/j.1399-0039.2012.01866.x

Abstract

The new allele shows one nucleotide change from C*07:02:01:01 at 351 nt from C to A, resulting in an amino acid change at codon 93 of exon 3 from H to Q.

MeSH terms

Alleles*
Amino Acid Sequence
DNA Probes, HLA / genetics
Exons / genetics*
HLA-C Antigens / genetics*
Hematopoietic Stem Cell Transplantation
Histocompatibility Testing
Humans
Italy
Molecular Sequence Data
Mutation / genetics*
Polymorphism, Single Nucleotide
Sequence Analysis, DNA
Tissue Donors

Substances

DNA Probes, HLA
HLA-C Antigens