Intra-operative management of low portal vein flow in pediatric living donor liver transplantation

Transpl Int. 2012 May;25(5):586-91. doi: 10.1111/j.1432-2277.2012.01464.x. Epub 2012 Mar 26.

Abstract

For pediatric living donor liver transplantation, portal vein complications cause significant morbidity and graft failure. Routine intra-operative Doppler ultrasound is performed after graft reperfusion to evaluate the flow of portal vein. This retrospective study reviewed 65 children who had undergone living donor liver transplantation. Seven patients were detected with suboptimal portal vein flow velocity following vascular reconstruction and abdominal closure. They underwent immediate on-table interventions to improve the portal vein flow. Both surgical and endovascular modalities were employed, namely, graft re-positioning, collateral shunt ligation, thrombectomy, revision of anastomosis, inferior mesenteric vein cannulation, and endovascular stenting. The ultrasonographic follow-up assessment for all seven patients demonstrated patent portal vein and satisfactory flow. We reviewed our experience on the different modalities and proposed an approach for our future intra-operative management to improve portal vein flow at the time of liver transplantation.

MeSH terms

  • Blood Flow Velocity
  • Endovascular Procedures
  • Female
  • Humans
  • Infant
  • Intraoperative Complications / physiopathology
  • Intraoperative Complications / surgery*
  • Intraoperative Complications / therapy*
  • Liver Transplantation / adverse effects*
  • Liver Transplantation / methods*
  • Living Donors
  • Male
  • Portal Vein / diagnostic imaging
  • Portal Vein / physiopathology*
  • Portal Vein / surgery
  • Retrospective Studies
  • Ultrasonography, Doppler