[Is there a benefit to continue pap smear screening for cervical cancer after 65 years of age? A retrospective study on 53,644 women]

Bull Cancer. 2012 Apr 1;99(4):409-15. doi: 10.1684/bdc.2012.1556.
[Article in French]

Abstract

Background: One third of cervical cancers are discovered after age 65. French guidelines allow women to cease having cervical pap smears at age 65, providing they have had a minimum of two consecutive negative smears.

Aim: To study the frequency of pathological smears in the group of women aged over 65 with a normal and sufficient cytological follow-up, according to the guidelines. To analyze the smear results and the former follow-up of this population to determine whether there is an interest to continue the smear screening after age 65.

Methods: This is a retrospective multicenter study based on collecting data from three pathology laboratories of the region Rhone-Alpes. We study a population of women 65 and older with smears that have been made between 2004 and 2008.

Results: Precancerous lesions and cervical cancer can be discovered after age 65 despite an adequate former follow-up. The rate of these women for having a pathological smear is 14,2‰, including 1,2‰ with cytological abnormalities in favour of cancer.

Conclusion: These results show that there is interest to continue the smear tests after age 65 at least, while considering medical and financial issues of a reasonable screening strategy.

Publication types

  • Multicenter Study

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Female
  • France / epidemiology
  • Humans
  • Papanicolaou Test*
  • Precancerous Conditions / epidemiology
  • Precancerous Conditions / pathology*
  • Retrospective Studies
  • Uterine Cervical Neoplasms / epidemiology
  • Uterine Cervical Neoplasms / pathology*
  • Vaginal Smears / statistics & numerical data*