Human parvovirus PARV4 in plasma pools of Chinese origin

Vox Sang. 2012 Oct;103(3):183-5. doi: 10.1111/j.1423-0410.2012.01605.x. Epub 2012 Mar 27.

Abstract

Human parvovirus 4 (PARV4) is present in blood and blood products. As the presence and levels of PARV4 in Chinese source plasma pools have never been determined, we implemented real-time quantitative PCR to investigate the presence of PARV4 in source plasma pools in China. Results showed that 26·15% (51/195) of lots tested positive for PARV4. The amounts of DNA ranged from 2·83 × 10(3) copies/ml to 2·35×10(7) copies/ml plasma. The high level of PARV4 in plasma pools may pose a potential risk to recipients. Further studies on the pathogenesis of PARV4 are urgently required.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asian People
  • Humans
  • Parvoviridae Infections / blood*
  • Parvoviridae Infections / genetics
  • Parvoviridae Infections / virology*
  • Parvovirus / genetics
  • Parvovirus / immunology
  • Parvovirus / isolation & purification*
  • Real-Time Polymerase Chain Reaction