Abstract
To determine possible cosavirus association with clinical disease, we used real-time reverse transcription PCR to test children and HIV-positive adults in Brazil with and without gastroenteritis. Thirteen (3.6%) of 359 children with gastroenteritis tested positive, as did 69 (33.8%) of 204 controls. Low prevalence, frequent viral co-infections, and low fecal cosavirus RNA concentrations argue against human pathogenicity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Brazil / epidemiology
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Case-Control Studies
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Child
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Cohort Studies
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Coinfection
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Diarrhea / epidemiology*
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Diarrhea / virology
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Feces / virology
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Gastroenteritis / epidemiology*
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Gastroenteritis / virology
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Genes, Viral
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Humans
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Molecular Sequence Data
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Picornaviridae / genetics
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Picornaviridae / isolation & purification*
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Picornaviridae Infections / epidemiology*
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Picornaviridae Infections / virology
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Prevalence
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Sequence Analysis, DNA
Associated data
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GENBANK/JN228118
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GENBANK/JN228188