Results of fractionated TBI prior to bone marrow transplantation in standard risk leukaemia at Marseille

Radiother Oncol. 1990:18 Suppl 1:132-4. doi: 10.1016/0167-8140(90)90193-z.

Abstract

One hundred and six patients with standard risk leukaemia were given fractionated TBI prior to allogeneic (72 cases, 27 of whom were T-depleted) or autologous (34 cases) bone marrow transplantation (BMT). Disease free survival at 5 years is 68% for allogeneic non T-depleted BMT and 33% for T-depleted BMT. Deaths are related to relapse, GVHD, infections, pneumonitis, encephalitis, VOD, AIDS, rejection.

MeSH terms

  • Adolescent
  • Adult
  • Bone Marrow Transplantation* / adverse effects
  • Clinical Protocols
  • Combined Modality Therapy
  • Humans
  • Leukemia / mortality
  • Leukemia / radiotherapy*
  • Leukemia / surgery
  • Lymphocyte Depletion
  • Neoplasm Recurrence, Local
  • Radiotherapy Dosage
  • T-Lymphocytes
  • Whole-Body Irradiation / methods*