Rare variety of T-cell lymphoma

J Assoc Physicians India. 2011 Oct:59:667-8.

Abstract

We report a case of 18 year old male who presented with hepatosplenomegaly, anemia and thrombocytopenia. His complete hemogram, peripheral smear, bone marrow studies were inconclusive. On immunophenotyping he was diagnosed as "Hepatosplenic gamma delta (gammadelta) T cell lymphoma" which is a very rare variety of T cell lymphoma. Less than 100 cases have been described in the literature since the entity was first described in 1990.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols
  • Biopsy
  • Bone Marrow / pathology
  • Cyclophosphamide
  • Doxorubicin
  • Follow-Up Studies
  • Hepatomegaly / pathology
  • Humans
  • Immunophenotyping
  • Liver Neoplasms / drug therapy
  • Liver Neoplasms / pathology*
  • Lymphoma, T-Cell / drug therapy
  • Lymphoma, T-Cell / pathology*
  • Male
  • Prednisolone
  • Receptors, Antigen, T-Cell, gamma-delta / analysis*
  • Receptors, Antigen, T-Cell, gamma-delta / genetics
  • Splenic Neoplasms / drug therapy
  • Splenic Neoplasms / pathology*
  • Splenomegaly / pathology
  • Vincristine

Substances

  • Receptors, Antigen, T-Cell, gamma-delta
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisolone

Supplementary concepts

  • VAP-cyclo protocol