The authors submit their experience with the examination of immunoglobulins and albumin in the faeces of patients with different diseases of the gastrointestinal tract. The presence of antibodies IgA, sIgA, IgM and albumin were assessed in lavages from the rectum or supernatant of the faeces, using the qualitative method of double immunodifussion according to Ouchterlony. A normal finding is characterized by the presence of IgA, sIgA. For evaluation of the clinical importance and applicability of the examination method the authors draw attention to the importance of asessing the degree of positive or negative correlation between findings and the final diagnosis. The authors present three basic pictures; acute inflammation, chronic inflammation, non-inflammatory exsudation (exsudative enteropathy). They analyze the clinical application of different findings and their practical impact. They give an account of limiting factors in the evaluation of the presence of immunoglobulins and albumin in faeces.