Immune reconstitution inflammatory syndrome of Kaposi's sarcoma in an HIV-infected patient

J Microbiol Immunol Infect. 2013 Aug;46(4):309-12. doi: 10.1016/j.jmii.2012.01.006. Epub 2012 Apr 12.

Abstract

We present a case of Kaposi's sarcoma-related immune reconstitution inflammatory syndrome in an HIV-infected patient who developed fever, worsening pulmonary infiltrates with respiratory distress, and progression of skin tumors at the popliteal region and thigh that resulted in limitation on movement of the right knee joint at 3.5 months following a significant increase of CD4 count after combination antiretroviral therapy.

Keywords: Combination antiretroviral therapy; HIV infection; Human herpes virus 8; Immune reconstitution inflammatory syndrome; Kaposi’s sarcoma.

Publication types

  • Case Reports

MeSH terms

  • Anti-Retroviral Agents / therapeutic use*
  • CD4 Lymphocyte Count
  • HIV Infections / complications*
  • HIV Infections / drug therapy*
  • Humans
  • Immune Reconstitution Inflammatory Syndrome / diagnosis*
  • Immune Reconstitution Inflammatory Syndrome / pathology
  • Male
  • Middle Aged
  • Radiography, Thoracic
  • Sarcoma, Kaposi / diagnosis*
  • Sarcoma, Kaposi / pathology

Substances

  • Anti-Retroviral Agents