[A case of lung metastases of carcinoma of the ampulla of vater effectively treated with S-1]

Gan To Kagaku Ryoho. 2012 Apr;39(4):637-9.
[Article in Japanese]

Abstract

A 70-year-old female patient underwent pylorus-preserving pancreaticoduodenectomy for carcinoma of the ampulla of Vater in March 2007. In April 2009, multiple lung metastases were detected by CT scanning. The patient was treated with S-1 (80mg/day, day 1-28, followed by 2-weeks withdrawal)from April 2009. The shrinkage of lung metastases was diagnosed as a complete response based on the Response Evaluation Criteria in Solid Tumors(RECIST). No severe toxicities were observed. S-1 is an effective and safe anti-cancer agent available for lung metastases of carcinoma of the ampulla of Vater.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Aged
  • Ampulla of Vater*
  • Antimetabolites, Antineoplastic / therapeutic use*
  • Common Bile Duct Neoplasms / drug therapy*
  • Common Bile Duct Neoplasms / pathology
  • Common Bile Duct Neoplasms / surgery
  • Drug Combinations
  • Duodenal Neoplasms / drug therapy*
  • Duodenal Neoplasms / pathology
  • Duodenal Neoplasms / surgery
  • Female
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / secondary
  • Oxonic Acid / therapeutic use*
  • Pancreatic Neoplasms / drug therapy*
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / surgery
  • Tegafur / therapeutic use*
  • Tomography, X-Ray Computed

Substances

  • Antimetabolites, Antineoplastic
  • Drug Combinations
  • S 1 (combination)
  • Tegafur
  • Oxonic Acid