Abstract
To provide an early estimate of 2011/12 influenza vaccine effectiveness (VE), we conducted a multicentre case-control study based on seven sentinel surveillance networks. We included influenza-like illness cases up to week 7/2012 from the vaccination target groups, swabbed less than eight days after symptom onset. Laboratory-confirmed influenza A(H3) cases were compared to negative controls. Adjusted VE was 43% (95% confidence interval: -0.4 to 67.7), suggesting low to moderate VE against influenza A(H3) in the early 2011/12 season.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Case-Control Studies
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Child
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Child, Preschool
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Confidence Intervals
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Disease Outbreaks / prevention & control*
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Disease Outbreaks / statistics & numerical data
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Europe / epidemiology
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Female
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Humans
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Infant
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Infant, Newborn
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Influenza A Virus, H1N1 Subtype / immunology*
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Influenza A Virus, H1N1 Subtype / isolation & purification
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Influenza Vaccines / administration & dosage*
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Influenza Vaccines / immunology
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Influenza, Human / epidemiology
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Influenza, Human / prevention & control*
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Influenza, Human / virology
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Male
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Middle Aged
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Seasons
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Sentinel Surveillance
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Treatment Outcome
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Vaccination / statistics & numerical data*
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Young Adult