CT cisternography in intracranial symptomatic arachnoid cysts: classification and treatment

J Neurol Sci. 2012 Jul 15;318(1-2):125-30. doi: 10.1016/j.jns.2012.03.008. Epub 2012 Apr 19.

Abstract

Objectives: The symptom and neuroimaging as indications for treating arachnoid cysts (ACs) are not adequate. Understanding the communication between cyst and subarachnoid space is helpful for decision-making. We took a dynamic study of ACs using CT cisternography (CTC) and proposed a classification of arachnoid cysts.

Materials and methods: Total 52 symptomatic patients with ACs were enrolled in this prospective study. CTC images were ordered, in all enrolled patients, at the 1, 3, 6, 12, 24 and 48 h after the intrathecal Omnipaque administration. Enhancement in cysts was measured quantitatively and was compared with neighboring subarachnoid spaces. All enrolled patients were allocated randomly in 2 groups. The CTC result was considered before treatment in one group (CTC group), while another group was surgically treated without considering CTC results (surgical group).

Results: ACs in our study were classified into 3 types: complete (cyst filling time at 1 h), incomplete (filling time began at 3 h) and noncommunicating cysts (no or slight filling after 24 h). Twenty-two patients in CTC group with incomplete communicating, or noncommunicating cysts underwent surgeries. And other 6 patients with complete communicating cysts were closely observed. In CTC group, the symptom of all surgical patients was relieved, and 5 out of 6 observational patients showed clinical improvement or no deterioration during the follow-up. In surgical group, only 18 out of 24 patients showed clinical improvement after surgeries, and there were 6 patients showing no difference before and after surgeries in symptom and in imaging.

Conclusions: This classification based on dynamic CT cisternography is useful for the decision of surgical indication. Some symptomatic patients with complete communicating ACs may not need surgical intervention.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Arachnoid Cysts / classification*
  • Arachnoid Cysts / diagnostic imaging*
  • Arachnoid Cysts / surgery
  • Brain / diagnostic imaging*
  • Brain / pathology
  • Brain / surgery
  • Child
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neurosurgical Procedures / standards*
  • Prospective Studies
  • Subarachnoid Space / diagnostic imaging*
  • Subarachnoid Space / pathology
  • Subarachnoid Space / surgery
  • Tomography, X-Ray Computed / methods*
  • Young Adult