TRPV1 antagonists: clinical setbacks and prospects for future development

Prog Med Chem. 2012:51:57-70. doi: 10.1016/B978-0-12-396493-9.00002-9.
No abstract available

Publication types

  • Review

MeSH terms

  • Analgesics, Non-Narcotic / chemistry
  • Analgesics, Non-Narcotic / pharmacology
  • Analgesics, Non-Narcotic / therapeutic use
  • Benzimidazoles / pharmacology*
  • Benzothiazoles / pharmacology*
  • Benzothiazoles / therapeutic use
  • Body Temperature Regulation / drug effects
  • Humans
  • Indazoles / pharmacology*
  • Pyridines / pharmacology*
  • Pyrimidines / pharmacology*
  • Pyrimidines / therapeutic use
  • Pyrrolidines / pharmacology*
  • TRPV Cation Channels / antagonists & inhibitors*
  • Urea / analogs & derivatives*
  • Urea / pharmacology

Substances

  • ABT 102
  • AZD1386
  • Analgesics, Non-Narcotic
  • Benzimidazoles
  • Benzothiazoles
  • Indazoles
  • MK-2295
  • N-(4-(6-(4-trifluoromethylphenyl)pyrimidin-4-yloxy)benzothiazol-2-yl)acetamide
  • Pyridines
  • Pyrimidines
  • Pyrrolidines
  • SB 705498
  • TRPV Cation Channels
  • TRPV1 protein, human
  • Urea