Kinetics of CMV seroconversion in a Swiss pregnant women population

Gregory T Maine; René Stricker; Reto Stricker

doi:10.1016/j.diagmicrobio.2012.03.016

Kinetics of CMV seroconversion in a Swiss pregnant women population

Diagn Microbiol Infect Dis. 2012 Jul;73(3):275-7. doi: 10.1016/j.diagmicrobio.2012.03.016. Epub 2012 Apr 27.

Authors

Gregory T Maine¹, René Stricker, Reto Stricker

Affiliation

¹ Abbott Diagnostics, Abbott Park, IL 60064, USA. [email protected]

PMID: 22541330
DOI: 10.1016/j.diagmicrobio.2012.03.016

Abstract

Retrospective evaluation of the kinetics of cytomegalovirus (CMV) seroconversion with CMV IgM, IgG, and IgG avidity assays, in a Swiss pregnant women population, has shown that the current published CMV serologic diagnostic algorithms were valid and fit for use. In 19% of the cases analyzed, CMV-specific IgM was detected before IgG.

MeSH terms

Adult
Antibodies, Viral / blood*
Antibody Affinity
Cytomegalovirus / immunology*
Cytomegalovirus Infections / diagnosis*
Cytomegalovirus Infections / immunology*
Female
Humans
Immunoglobulin G / blood
Immunoglobulin M / blood
Pregnancy
Pregnancy Complications, Infectious / diagnosis*
Pregnancy Complications, Infectious / immunology*
Retrospective Studies
Switzerland

Substances

Antibodies, Viral
Immunoglobulin G
Immunoglobulin M