Oncologic outcome in surgical management of jugular paraganglioma and factors influencing outcomes

Head Neck. 2013 Apr;35(4):527-34. doi: 10.1002/hed.22987. Epub 2012 Apr 27.

Abstract

Background: The purpose of this study was to identify the factors that may influence the management outcome in patients with jugular paragangliomas.

Methods: The surgical records of 121 cases of jugular paraganglioma (Fisch classifications C and D) were reviewed.

Results: The average follow-up was 88 months. Intracranial extension (ICE; Fisch classification De and Di) constitutes 55.4% of the cases. Two cases had a malignant jugular paraganglioma. Complete tumor resection was achieved in 81.8% of the cases, and there was evidence of recurrence in 4.0% from this group. Surgical tumor control was achieved in 96% of cases. Perioperative complications consisted mainly of cerebrospinal fluid leakage in 1.6% of the cases. The lower cranial nerve (CN) was preserved in 63% of the patients mainly in the cases without ICE.

Conclusion: The infratemporal fossa approach type A allows for complete tumor resection with low perioperative morbidity and recurrence rates. The significant influential factors were the severity of ICE and internal carotid artery involvement.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cranial Nerves / pathology*
  • Cranial Nerves / surgery
  • Female
  • Follow-Up Studies
  • Glomus Jugulare Tumor / pathology
  • Glomus Jugulare Tumor / surgery*
  • Glomus Jugulare Tumor / therapy
  • Humans
  • Jugular Veins / pathology*
  • Male
  • Middle Aged
  • Postoperative Complications / etiology*
  • Skull Base Neoplasms / pathology
  • Skull Base Neoplasms / surgery*
  • Treatment Outcome
  • Young Adult