Enforcing silencing: dynamic HP1 complexes in Neurospora

Nat Struct Mol Biol. 2012 May 3;19(5):465-7. doi: 10.1038/nsmb.2291.

Abstract

Analysis of the Neurospora crassa chromodomain protein CDP-2, a component of a newly characterized HP1-containing complex, reveals a second gene-silencing mechanism and provides insights into the dynamic nature of chromatin domains that possess shared components.

MeSH terms

  • Chromobox Protein Homolog 5
  • Chromosomal Proteins, Non-Histone / chemistry
  • Chromosomal Proteins, Non-Histone / genetics*
  • Chromosomal Proteins, Non-Histone / metabolism
  • Fungal Proteins / chemistry
  • Fungal Proteins / genetics*
  • Fungal Proteins / metabolism
  • Gene Silencing*
  • Heterochromatin / genetics
  • Heterochromatin / metabolism
  • Neurospora crassa / chemistry
  • Neurospora crassa / genetics*
  • Neurospora crassa / metabolism
  • Protein Structure, Tertiary

Substances

  • Chromosomal Proteins, Non-Histone
  • Fungal Proteins
  • Heterochromatin
  • Chromobox Protein Homolog 5