Abstract
In this study, we compared lesion size by using VADC and VT2 at 0, 2, 5, 24, and 48 hours and histologic lesions at 48 hours in a P7 rat stroke model. The best correlation between VHISTO and VADC was at H0, and between VHISTO and VT2, at H2-H5. Early MR imaging signals allowed excluding "no-lesion" and "no-reflow" animals to help standardize this neonatal stroke model and predict lesion size.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Animals, Newborn
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Brain Ischemia / diagnosis*
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Brain Ischemia / pathology
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Carotid Artery, Common / pathology
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Disease Models, Animal
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Echo-Planar Imaging / methods
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Forecasting
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Hypoxia-Ischemia, Brain / diagnosis
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Hypoxia-Ischemia, Brain / pathology
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Image Processing, Computer-Assisted / methods
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Magnetic Resonance Angiography / methods
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Magnetic Resonance Imaging / methods*
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Middle Cerebral Artery / pathology
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Prognosis
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Rats
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Rats, Wistar
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Reperfusion / methods
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Stroke / diagnosis*
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Stroke / pathology
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Time Factors