Refractory pyoderma gangrenosum of the orbit and the lacrimal sac

Orbit. 2012 Aug;31(4):249-51. doi: 10.3109/01676830.2011.648810. Epub 2012 May 9.

Abstract

Pyoderma gangrenosum (PG) is a rare, idiopathic, necrotizing, and non-infectious ulcerating skin disease included among the neutrophilic dermatoses. It rarely affects the eye, orbit, and/or ocular adnexa. We describe one case of PG affecting both orbits and the lacrimal sac in a patient with Crohn's disease.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adult
  • Crohn Disease / complications
  • Cyclophosphamide / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lacrimal Apparatus Diseases / diagnosis
  • Lacrimal Apparatus Diseases / drug therapy
  • Lacrimal Apparatus Diseases / etiology*
  • Magnetic Resonance Imaging
  • Methylprednisolone / therapeutic use
  • Orbital Diseases / diagnosis
  • Orbital Diseases / drug therapy
  • Orbital Diseases / etiology*
  • Prednisone / therapeutic use
  • Pulse Therapy, Drug
  • Pyoderma Gangrenosum / diagnosis
  • Pyoderma Gangrenosum / drug therapy
  • Pyoderma Gangrenosum / etiology*
  • Visual Acuity

Substances

  • Glucocorticoids
  • Immunosuppressive Agents
  • Cyclophosphamide
  • Prednisone
  • Methylprednisolone