KRAS oncogene rearrangements and gene fusions: unexpected rare encounters in late-stage prostate cancers

Cancer Discov. 2011 Jun;1(1):12-3. doi: 10.1158/2159-8274.CD-11-0045. Epub 2011 Jun 1.

Abstract

Wang and colleagues identify a fusion between UBE2L3 and KRAS in a subset of metastatic prostate cancers.

Publication types

  • Comment

MeSH terms

  • Animals
  • Gene Rearrangement*
  • Humans
  • Male
  • Prostatic Neoplasms / genetics*
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins p21(ras) / genetics*
  • ras Proteins / genetics*

Substances

  • KRAS protein, human
  • Proto-Oncogene Proteins
  • Hras protein, mouse
  • Proto-Oncogene Proteins p21(ras)
  • ras Proteins