Isolated corneal pseudodendrites as the initial manifestation of tyrosinemia type II in monozygotic twins

J Pediatr Ophthalmol Strabismus. 2012 May 8:49 Online:e33-6. doi: 10.3928/01913913-20120501-03.

Abstract

Fifteen-month-old twins presented with photophobia and bilateral corneal pseudodendrites, and tyrosinemia type II was suspected. Plasma tyrosine levels were elevated. After therapy with tyrosine-restricted diet, corneal lesions resolved. Bilateral pseudodendritic keratitis may be the initial or only manifestation of tyrosinemia type II.

Publication types

  • Case Reports

MeSH terms

  • Blepharospasm / diagnosis
  • Corneal Diseases / diagnosis*
  • Corneal Diseases / diet therapy
  • Corneal Diseases / genetics
  • Dendrites / pathology*
  • Diet, Protein-Restricted
  • Diseases in Twins / diagnosis*
  • Diseases in Twins / diet therapy
  • Diseases in Twins / genetics
  • Humans
  • Infant
  • Male
  • Photophobia / diagnosis
  • Twins, Monozygotic*
  • Tyrosine / blood
  • Tyrosinemias / diagnosis*
  • Tyrosinemias / diet therapy
  • Tyrosinemias / genetics

Substances

  • Tyrosine