Dermatomyositis and chest radiography leading to the diagnosis of lung cancer and subsequent confusions in staging due to the presence of tuberculosis

BMJ Case Rep. 2012 Apr 2:2012:bcr0120125585. doi: 10.1136/bcr.01.2012.5585.

Abstract

This clinical scenario describes dermatomyositis as a presenting feature of carcinoma of the lung. However, the coincident existence of tuberculosis in the opposite lung gave rise to a false impression of contralateral lung metastasis and hence confusions with regard to staging ensued, which were clarified after further investigation confirmed a unilateral lung adenocarcinoma and contralateral tuberculosis. The patient was initiated on oral antiepidermal growth factor receptor therapy with erlotinib, as well as on multi-drug therapy for tuberculosis. This report intends to illustrate that paraneoplastic syndromes such as dermatomyositis can be the presenting feature of lung cancer, and also that the co-incident presence of carcinoma and tuberculosis can cause confusions with regard to staging and management.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antitubercular Agents / therapeutic use
  • Dermatomyositis / diagnostic imaging*
  • Diagnosis, Differential
  • Erlotinib Hydrochloride
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / drug therapy
  • Male
  • Neoplasm Staging
  • Protein Kinase Inhibitors / therapeutic use
  • Quinazolines / therapeutic use
  • Radiography, Thoracic
  • Tomography, X-Ray Computed
  • Tuberculosis, Pulmonary / diagnostic imaging*
  • Tuberculosis, Pulmonary / drug therapy

Substances

  • Antitubercular Agents
  • Protein Kinase Inhibitors
  • Quinazolines
  • Erlotinib Hydrochloride