A feasible shortcut for the mobilization outcome: Steady state CD34 positive hematopoietic stem cells

Transfus Apher Sci. 2012 Aug;47(1):67-75. doi: 10.1016/j.transci.2012.05.003. Epub 2012 May 31.

Abstract

Predicting success of hematopoietic cell mobilization is an important issue for transplant physicians. We examined the steady state peripheral blood CD34+ cell count to predict ability to mobilize adequate hematopoietic progenitor cells in 63 myeloma and lymphoma patients. The median steady state CD34+ cell number was 1.56/μL (0.03-5.76). Although counting steady state CD34+ is definitely cost effective to predict the successful mobilization, we could not find a threshold steady state CD34 count of any value predicting successful mobilization.

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Hematopoietic Stem Cell Mobilization / methods*
  • Hematopoietic Stem Cells*
  • Humans
  • Leukocyte Count
  • Lymphoma*
  • Male
  • Middle Aged
  • Multiple Myeloma*
  • Peripheral Blood Stem Cell Transplantation
  • Transplantation, Autologous