Can we trust studies published by authors with financial conflicts? Using the decline of metal-on-metal total hip arthroplasty to investigate

J Arthroplasty. 2012 Sep;27(8 Suppl):41-5.e1. doi: 10.1016/j.arth.2012.03.060. Epub 2012 Jun 6.

Abstract

The objective of our study was to determine if authors with conflicts of interest are less likely to report negative study outcomes in metal-on-metal total hip arthroplasty. We performed a systematic review of 3 major orthopedic journals for articles related to metal-on-metal total hip arthroplasty over 12 years. A total of 64 studies reported clinical outcomes and were included. Reviewers assigned a positive, neutral, or negative label. Each study was noted for the presence of absence of a financial conflict. There was a significant trend from positive to negative study outcomes over time (P = .015). A similar negative trend was seen in studies written by authors with financial disclosures (P = .021). Authors with financial conflicts have contributed to the increase in negative outcomes reported in the literature.

Publication types

  • Review
  • Systematic Review

MeSH terms

  • Arthroplasty, Replacement, Hip*
  • Authorship / standards*
  • Conflict of Interest*
  • Disclosure*
  • Hip Prosthesis*
  • Humans
  • Metal-on-Metal Joint Prostheses*
  • Publishing / standards*
  • Treatment Failure
  • United States