In the last decade we have witnessed a stormy development in the field of molecular biology, immunology and genetics. Dramatic advances in laboratory and clinical procedures in cellular immunotherapy, along with the development of powerful immunomodulatory agents, created new conditions and opportunities in the treatment of ovarian cancer. The review article provides an overview of the current state of immunotherapy, outlines modern trends in the development of vaccines and immunomodulatory therapies available for immediate clinical testing in cases of advanced ovaria cancer.