Hyperpigmentation of the hard palate associated with imatinib therapy for chronic myeloid leukemia with a genetic variation in the proto-oncogene c-KIT

Leuk Lymphoma. 2013 Jan;54(1):186-8. doi: 10.3109/10428194.2012.702904. Epub 2012 Aug 14.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Antineoplastic Agents / therapeutic use
  • Base Sequence
  • Benzamides / adverse effects*
  • Benzamides / therapeutic use
  • Female
  • Genetic Variation
  • Heterozygote
  • Humans
  • Hyperpigmentation / chemically induced*
  • Imatinib Mesylate
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
  • Middle Aged
  • Mutation
  • Palate, Hard / pathology*
  • Piperazines / adverse effects*
  • Piperazines / therapeutic use
  • Proto-Oncogene Mas
  • Proto-Oncogene Proteins c-kit / genetics
  • Pyrimidines / adverse effects*
  • Pyrimidines / therapeutic use

Substances

  • Antineoplastic Agents
  • Benzamides
  • MAS1 protein, human
  • Piperazines
  • Proto-Oncogene Mas
  • Pyrimidines
  • Imatinib Mesylate
  • Proto-Oncogene Proteins c-kit