Hyperosmolar non-ketotic hyperglycaemia: an important and reversible cause of acute bilateral ballismus

BMJ Case Rep. 2012 Jun 21:2012:bcr1120115084. doi: 10.1136/bcr-11-2011-5084.

Abstract

An 83-year-old lady with type 2 diabetes mellitus was admitted to hospital with pneumonia. After 3 days of oral amoxicillin she developed ballism-choreiform movements of all four limbs. Her serum glucose and osmolality were raised. She had no factors suggestive of genetic or iatrogenic causes. A CT scan of the brain revealed bilateral putamen hyperintensities. She was started on tetrabenazine and subcutaneous insulin, which led to complete resolution of her symptoms.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adrenergic Uptake Inhibitors
  • Aged, 80 and over
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetes Mellitus, Type 2 / drug therapy
  • Dyskinesias / drug therapy
  • Dyskinesias / etiology*
  • Female
  • Humans
  • Hyperglycemia / blood*
  • Hyperglycemia / complications*
  • Hyperglycemia / drug therapy
  • Insulin / therapeutic use
  • Osmolar Concentration
  • Tetrabenazine / therapeutic use

Substances

  • Adrenergic Uptake Inhibitors
  • Insulin
  • Tetrabenazine