Hemostatic modifications of the Bentall procedure: imbricated proximal suture and fibrin sealant reduce postoperative morbidity and mortality rates

Tex Heart Inst J. 2012;39(2):206-10.

Abstract

Bleeding is an important predictor of morbidity and mortality rates after the Bentall operation. This study reports our recent experience with composite aortic root replacement via a slightly modified button-Bentall operation. Fifty-six consecutive patients underwent a Bentall operation on an elective basis from January 2008 through December 2009. In all cases, we used 2 modifications: we imbricated the pledgeted 2-0 polyester interrupted U stitches of the proximal suture line, and at that same suture line we sealed with fibrin glue the possible sources of oozing. The series featured high proportions of associated procedures (25%) and reoperations (23%). The mean cardiopulmonary bypass and aortic cross-clamp times were 166 ± 50 and 113 ± 27 min, respectively. No case of operative or hospital (30-day) death was observed. Postoperative drainage amounted to 705 mL (median) on the first postoperative day and 377 mL (mean) on the second. Surgical re-exploration for bleeding was needed in only 1 patient (1.8%). Postoperative acute kidney injury was observed in 5 patients, neurologic complications in 3, and respiratory insufficiency requiring prolonged mechanical ventilation in another 3. Both respiratory and renal complications were significantly associated with greater consumption of blood products (P=0.03 and P=0.001, respectively). We conclude that the combined use of imbricated proximal suture-line stitches and subsequent fibrin-sealant spraying were associated with no deaths and with low rates of bleeding and other adverse postoperative sequelae in our 2-year experience with the Bentall operation in an elective series of patients characterized by a difficult mixture of prognoses.

Keywords: Anastomosis, surgical; aorta/surgery; aortic aneurysm/surgery; blood vessel prosthesis implantation; fibrin tissue adhesive;; heart valve prosthesis; hemostasis, surgical/methods; suture techniques; tissue adhesives.

MeSH terms

  • Acute Kidney Injury / etiology
  • Adult
  • Aged
  • Aortic Aneurysm / mortality
  • Aortic Aneurysm / surgery*
  • Blood Vessel Prosthesis Implantation / adverse effects
  • Blood Vessel Prosthesis Implantation / methods*
  • Blood Vessel Prosthesis Implantation / mortality
  • Female
  • Fibrin Tissue Adhesive / therapeutic use*
  • Heart Valve Prosthesis Implantation / adverse effects
  • Heart Valve Prosthesis Implantation / methods*
  • Heart Valve Prosthesis Implantation / mortality
  • Hemostatic Techniques* / adverse effects
  • Hemostatic Techniques* / mortality
  • Humans
  • Italy
  • Male
  • Middle Aged
  • Nervous System Diseases / etiology
  • Postoperative Hemorrhage / etiology
  • Postoperative Hemorrhage / mortality
  • Postoperative Hemorrhage / prevention & control*
  • Reoperation
  • Respiration, Artificial
  • Respiratory Insufficiency / etiology
  • Respiratory Insufficiency / therapy
  • Retrospective Studies
  • Suture Techniques* / adverse effects
  • Suture Techniques* / mortality
  • Time Factors
  • Treatment Outcome

Substances

  • Fibrin Tissue Adhesive