Autoantibodies to the thyrotrophin receptor mimic thyrotrophin in stimulating both thyroglobulin and thyroid peroxidase mRNA transcription in human thyroid cells

Biochem Soc Trans. 1990 Aug;18(4):559-60. doi: 10.1042/bst0180559.

Authors

K S Collison¹, J P Banga, P S Barnett, G C Huang, A M McGregor

Affiliation

¹ Department of Medicine, King's College Hospital School of Medicine, Denmark Hill, London, U.K.

PMID: 2276434
DOI: 10.1042/bst0180559

No abstract available

MeSH terms

Autoantibodies / metabolism*
Cells, Cultured
Graves Disease / immunology
Graves Disease / metabolism
Humans
Iodide Peroxidase / genetics
RNA, Messenger / genetics
RNA, Messenger / metabolism
Receptors, Thyrotropin / immunology*
Thyroglobulin / genetics
Thyroid Gland / drug effects
Thyroid Gland / metabolism*
Thyrotropin / pharmacology
Transcription, Genetic / drug effects

Substances

Autoantibodies
RNA, Messenger
Receptors, Thyrotropin
Thyrotropin
Thyroglobulin
Iodide Peroxidase