Living kidney donor relationship in Caucasian and African American populations and implications for targeted donor education programs

Clin Transplant. 2013 Jan-Feb;27(1):32-6. doi: 10.1111/j.1399-0012.2012.01685.x. Epub 2012 Jul 9.

Abstract

Purpose: The opportunities for living kidney donation vary greatly among socioeconomic and racial groups. We reviewed our series of living donors to evaluate donor relationships in various groups.

Materials and methods: Donor and recipient records for 1000 patients were reviewed. An additional 857 records of potential recipients presenting with a donor were analyzed. We compared the relationship of the recipient to initial donor and individual who underwent nephrectomy.

Results: There were 693 CC and 263 AA live kidney donors. In the AA population donors were first-degree 71%, second-degree 10%, and unrelated 19%. In the CC population donors were first-degree 57%, second-degree 6%, and unrelated 37% (p < 0.0001 for unrelated CC vs. AA). Spousal donation is more common in CC donors (13%) than AA donors (6%), p = 0.001. Donation from child to parent is more common in AA (33%) than CC donors (15%), p < 0.0001. AA recipients predominantly identified a child as a donor in 63% and 48% were cleared for donation. In contrast, 69% of CC recipients identified a spouse as a donor yet only 23% became donors, p < 0.001 and p < 0.001.

Conclusions: There is a higher incidence of unrelated donors in the caucasian population, vs. first degree relatives often being living donors in the AA population.

MeSH terms

  • Black or African American / statistics & numerical data*
  • Child
  • Female
  • Follow-Up Studies
  • Graft Survival
  • Humans
  • Kidney Transplantation / psychology*
  • Living Donors / psychology*
  • Living Donors / statistics & numerical data
  • Male
  • Nephrectomy
  • Parents / education*
  • Prognosis
  • Prospective Studies
  • Spouses / education*
  • White People / statistics & numerical data*