Simultaneous infection of pigs and people with triple-reassortant swine influenza virus H1N1 at a U.S. county fair

Zoonoses Public Health. 2013 May;60(3):196-201. doi: 10.1111/j.1863-2378.2012.01508.x. Epub 2012 Jul 9.

Abstract

Influenza-like illness was noted in people and pigs in attendance at an Ohio county fair in August 2007. The morbidity rate in swine approached 100% within 1-2 days of initial clinical signs being recognized, and approximately two dozen people developed influenza-like illness. Triple-reassortant swine H1N1 influenza viruses were identified in both pigs and people at the fair. The identified viruses (A/Sw/OH/511445/2007, A/Ohio/01/2007, and A/Ohio/02/2007) were similar to H1N1 swine influenza viruses currently found in the U.S. swine population. This case illustrates the possibility of transmission of swine influenza in settings where there is close human/swine interaction.

MeSH terms

  • Animals
  • Antibodies, Viral / blood
  • Base Sequence
  • Chick Embryo
  • Dogs
  • Humans
  • Influenza A Virus, H1N1 Subtype / genetics
  • Influenza A Virus, H1N1 Subtype / immunology
  • Influenza A Virus, H1N1 Subtype / isolation & purification*
  • Influenza A Virus, H1N1 Subtype / physiology
  • Influenza, Human / epidemiology
  • Influenza, Human / transmission*
  • Influenza, Human / virology
  • Madin Darby Canine Kidney Cells
  • Molecular Sequence Data
  • Ohio / epidemiology
  • Orthomyxoviridae Infections / epidemiology
  • Orthomyxoviridae Infections / mortality
  • Orthomyxoviridae Infections / transmission*
  • Orthomyxoviridae Infections / virology
  • Phylogeny
  • RNA, Viral / genetics
  • Reassortant Viruses / genetics
  • Reassortant Viruses / isolation & purification*
  • Reassortant Viruses / physiology
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Swine
  • Swine Diseases / epidemiology
  • Swine Diseases / mortality
  • Swine Diseases / transmission*
  • Swine Diseases / virology
  • Zoonoses

Substances

  • Antibodies, Viral
  • RNA, Viral

Associated data

  • GENBANK/EU604691
  • GENBANK/EU604692
  • GENBANK/EU604693
  • GENBANK/EU604694
  • GENBANK/EU604695
  • GENBANK/EU604696
  • GENBANK/FJ986620
  • GENBANK/FJ986621