The movement protein encoded by gene 3 of rice transitory yellowing virus is associated with virus particles

J Gen Virol. 2012 Oct;93(Pt 10):2290-2298. doi: 10.1099/vir.0.044420-0. Epub 2012 Jul 18.

Abstract

Gene 3 in the genomes of several plant-infecting rhabdoviruses, including rice transitory yellowing virus (RTYV), has been postulated to encode a cell-to-cell movement protein (MP). Trans-complementation experiments using a movement-defective tomato mosaic virus and the P3 protein of RTYV, encoded by gene 3, facilitated intercellular transport of the mutant virus. In transient-expression experiments with the GFP-fused P3 protein in epidermal leaf cells of Nicotiana benthamiana, the P3 protein was associated with the nucleus and plasmodesmata. Immunogold-labelling studies of thin sections of RTYV-infected rice plants using an antiserum against Escherichia coli-expressed His(6)-tagged P3 protein indicated that the P3 protein was located in cell walls and on virus particles. In Western blots using antisera against E. coli-expressed P3 protein and purified RTYV, the P3 protein was detected in purified RTYV, whilst antiserum against purified RTYV reacted with the E. coli-expressed P3 protein. After immunogold labelling of crude sap from RTYV-infected rice leaves, the P3 protein, as well as the N protein, was detected on the ribonucleocapsid core that emerged from partially disrupted virus particles. These results provide evidence that the P3 protein of RTYV, which functions as a viral MP, is a viral structural protein and seems to be associated with the ribonucleocapsid core of virus particles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Wall / metabolism
  • Cell Wall / virology
  • Escherichia coli / genetics
  • Escherichia coli / metabolism
  • Nicotiana / genetics
  • Nicotiana / metabolism
  • Nicotiana / virology
  • Oryza / genetics*
  • Oryza / metabolism
  • Oryza / virology*
  • Plant Diseases / virology*
  • Plant Leaves / metabolism
  • Plant Leaves / virology
  • Plant Viral Movement Proteins / genetics*
  • Plant Viral Movement Proteins / metabolism
  • Plasmodesmata / metabolism
  • Plasmodesmata / virology
  • Rhabdoviridae / genetics*
  • Rhabdoviridae / metabolism
  • Tobamovirus / genetics
  • Tobamovirus / metabolism
  • Viral Proteins / genetics
  • Viral Proteins / metabolism
  • Viral Structural Proteins / genetics
  • Viral Structural Proteins / metabolism
  • Virion / genetics*
  • Virion / metabolism

Substances

  • Plant Viral Movement Proteins
  • Viral Proteins
  • Viral Structural Proteins