Single-incision surgery has higher cost with equivalent pain and quality-of-life scores compared with multiple-incision laparoscopic cholecystectomy: a prospective randomized blinded comparison

J Am Coll Surg. 2012 Nov;215(5):702-8. doi: 10.1016/j.jamcollsurg.2012.05.038. Epub 2012 Jul 21.

Abstract

Background: Since the development of single-incision surgery, several retrospective studies have demonstrated its feasibility; however, randomized prospective trials are still lacking. We report a prospective randomized single-blinded trial with a cost analysis of single-incision (SI) to multi-incision (MI) laparoscopic cholecystectomy.

Study design: After obtaining IRB approval, patients with chronic cholecystitis, acute cholecystitis, or biliary dyskinesia were offered participation in this multihospital, multisurgeon trial. Consenting patients were computer randomized into either a transumbilical SI or standard MI group; patient data were then entered into a prospective database.

Results: We report 79 patients that were prospectively enrolled and analyzed. Total hospital charges were found to be significantly different between SI and MI groups (MI $15,717 ± $14,231 vs SI $17,817 ± $5,358; p < 0.0001). Broken down further, the following subcharges were found to also be significant: operating room charges (MI $4,445 ± $1,078 vs SI $5,358 ± 893; p < 0.0001); medical/surgical supplies (MI $3,312 ± $6,526 vs SI $5,102 ± $1,529; p < 0.0001); and anesthesia costs (MI $579 ± $7,616 vs SI $820 ± $23,957; p < 0.0001). A validated survey (ie, Surgical Outcomes Measurement System) was used to evaluate various patient quality-of-life parameters at set visits after surgery; scores were statistically equivalent for fatigue, physical function, and satisfaction with results. No difference was found between visual analogue scale scores or inpatient and outpatient pain-medication use.

Conclusions: We show SI surgery to have higher costs than MI surgery with equivalent quality-of-life scores, pain analogue scores, and pain-medication use.

Publication types

  • Comparative Study
  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Analgesics / therapeutic use
  • Biliary Dyskinesia / economics
  • Biliary Dyskinesia / surgery*
  • Cholecystectomy, Laparoscopic / economics
  • Cholecystectomy, Laparoscopic / methods*
  • Cholecystitis / economics
  • Cholecystitis / surgery*
  • Female
  • Hospital Charges / statistics & numerical data*
  • Hospital Costs / statistics & numerical data
  • Humans
  • Intention to Treat Analysis
  • Male
  • Middle Aged
  • Pain Measurement
  • Pain, Postoperative / drug therapy
  • Pain, Postoperative / etiology*
  • Prospective Studies
  • Quality of Life*
  • Single-Blind Method
  • Surveys and Questionnaires
  • Treatment Outcome

Substances

  • Analgesics