Is intrapartum fever associated with ST-waveform changes of the fetal electrocardiogram? A retrospective cohort study

BJOG. 2012 Oct;119(11):1410-6. doi: 10.1111/j.1471-0528.2012.03442.x. Epub 2012 Jul 25.

Abstract

Objective: To investigate the association between maternal intrapartum fever and ST-waveform changes of the fetal electrocardiogram.

Design: Retrospective cohort study.

Setting: Three academic and six non-academic teaching hospitals in the Netherlands.

Population: Labouring women with a high-risk singleton pregnancy in cephalic position beyond 36 weeks of gestation.

Methods: We studied 142 women with fever (≥38.0°C) during labour and 141 women with normal temperature who had been included in two previous studies. In both groups, we counted the number and type of ST-events and classified them as significant (intervention needed) or not significant, based on STAN(®) clinical guidelines.

Main outcome measures: Number and type of ST-events.

Results: Both univariable and multivariable regression analysis showed no association between the presence of maternal intrapartum fever and the number or type of ST-events.

Conclusions: Maternal intrapartum fever is not associated with ST-segment changes of the fetal electrocardiogram. Interpretation of ST-changes in labouring women with fever should therefore not differ from other situations.

MeSH terms

  • Arrhythmias, Cardiac / diagnosis
  • Arrhythmias, Cardiac / etiology*
  • Cohort Studies
  • Electrocardiography / methods*
  • Female
  • Fetal Diseases / etiology*
  • Fetal Diseases / physiopathology
  • Fetal Monitoring / methods*
  • Fever / complications*
  • Heart Rate, Fetal
  • Humans
  • Labor, Obstetric
  • Logistic Models
  • Netherlands
  • Pregnancy
  • Pregnancy Complications* / diagnosis
  • Pregnancy, High-Risk
  • Retrospective Studies
  • Risk Factors