[COX-2 as an early diagnostic marker of virus-associated human malignant neoplasms]

S V Diduk; K V Smirnova; V É Gurtsevich

[COX-2 as an early diagnostic marker of virus-associated human malignant neoplasms]

Vopr Virusol. 2012 Mar-Apr;57(2):4-8.

[Article in Russian]

Authors

S V Diduk, K V Smirnova, V É Gurtsevich

PMID: 22834139

Abstract

The review analyzes recent data and current ideas on the enzyme cyclooxygenase 2 (COX-2) as a possible biomarker of virus-associated human malignant neoplasm. Possible mechanisms of COX-2 activation in the cells infected with oncogenic human viruses, such as hepatitis B virus, Epstein-Barr virus, and human papillomavirus are considered in detail.

Publication types

English Abstract
Review

MeSH terms

Biomarkers, Tumor / metabolism*
Cyclooxygenase 2 / metabolism*
Early Diagnosis
Hepatitis B virus / metabolism
Herpesvirus 4, Human / metabolism
Humans
Papillomaviridae / metabolism
Tumor Virus Infections / diagnosis*
Tumor Virus Infections / enzymology
Tumor Virus Infections / virology

Substances

Biomarkers, Tumor
Cyclooxygenase 2