Abstract
We reported on thirteen children affected with malformative syndromes associated with mental retardation. MRI examination showed in all of them different types of anomalies; agenesis of corpus callosum, ventricular dilatation and cerebral matter alterations were the most frequent findings. The authors give a brief description of the clinical reports and of the anomalies observed with MRI; they conclude that MRI seems to be a valuable tool especially for the study of the alterations of the cerebral matter and their correlation with mental retardation.
MeSH terms
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Abnormalities, Multiple* / pathology
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Acrocephalosyndactylia / pathology
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Adolescent
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Agenesis of Corpus Callosum
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Arnold-Chiari Malformation / pathology
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Brain / abnormalities*
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Brain / pathology
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Cerebral Ventricles / pathology
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Child
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Child, Preschool
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Corpus Callosum / pathology
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Dilatation, Pathologic
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Fetal Alcohol Spectrum Disorders / pathology
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Gigantism / pathology
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Hereditary Sensory and Motor Neuropathy / pathology
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Humans
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Infant
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Intellectual Disability / pathology*
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Magnetic Resonance Imaging*
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Noonan Syndrome / pathology
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Oculocerebrorenal Syndrome / pathology
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Syndrome