The study of the inter-metacarpophalangeal spaces on 20 human bodies raises the question of the existence of bursae at this level, in line with recent studies (BOSSEY, MIDY) suggesting that such bursae are present at the level of the foot. Careful dissection and histological studies revealed characteristics compatible with both of the following hypotheses: either there are bursae not described until now in anatomy textbooks, or these are virtual spaces limited by a cul-de-sac of the aponeuroses of the hand in the 2nd, 3rd and 4th spaces. Tissue analysis that could determine more specifically the nature of the limiting membrane of these spaces, as well as pathological studies demonstrating the occurrence of common anomalies of bursae in these spaces, are required in order to conclude definitively on the nature of the inter-metecarpophalangeal spaces.