CSF diversion in refractory idiopathic intracranial hypertension: single-centre experience and review of efficacy

Childs Nerv Syst. 2013 Feb;29(2):263-7. doi: 10.1007/s00381-012-1895-5. Epub 2012 Aug 24.

Abstract

Purpose: The current surgical management strategies for refractory cases of idiopathic intracranial hypertension (IIH) remain unresolved. We evaluated the outcome of our paediatric patients who were offered a CSF diversion procedure in order to control their symptoms.

Methods: We retrospectively reviewed the medical notes of the patients under 16 years of age, who presented in our centre from 2005 to 2010, with a confirmed diagnosis of IIH, and ultimately had a lumboperitoneal shunt (LPS). We describe their immediate postoperative course, shunt-related complications and recent outcome.

Results: Seven patients presented at a mean age of 8.7 years. Two presented with significant visual loss and had a shunt acutely; the remaining five presented with headaches and were shunted within 2 years. In the immediate postoperative period two patients experienced low-pressure symptoms. All patients required shunt revisions; in total 15 revisions took place, mainly secondary to symptomatic overdrainage or obstruction. After a mean follow-up of 26 months, two patients have diminished visual acuity at least on one side; only one patient became headache-free, despite resolution of the CSF pressure post diversion in four out of the six remaining patients.

Conclusions: All patients required shunt revisions and 6/7 (85.7%) had persisting headaches at their last follow-up. It is apparent that once functional, the LPS seems adequate to lower the CSF pressure but not effective in eliminating symptoms.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Cerebrospinal Fluid Shunts / methods*
  • Child
  • Child, Preschool
  • Cohort Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Pseudotumor Cerebri / cerebrospinal fluid*
  • Pseudotumor Cerebri / diagnosis
  • Pseudotumor Cerebri / surgery
  • Retrospective Studies
  • Treatment Outcome