[Hemicrania continua: characteristics and therapeutic experience in a series of 36 patients]

Rev Neurol. 2012 Sep 1;55(5):270-8.
[Article in Spanish]

Abstract

Introduction: Hemicrania continua is characterised by a continuous unilateral pain, which frequently gets worse in association with autonomic symptoms. It is probably little known and underdiagnosed. Its diagnosis requires a response to indomethacin, which is not always well tolerated.

Aims: We report a series of 36 cases of hemicrania continua that were treated in the headache service of a tertiary hospital. We analyse their demographic and clinical features and the therapeutic alternatives to indomethacin.

Patients and methods: Between January 2008 and April 2012, 36 patients (28 females, eight males) were diagnosed with hemicrania continua from among 1800 (2%) who were treated in that service.

Results: The age of onset was 46.3 ± 18.4 years. In four patients (11.1%) there were pain remissions that lasted over three months. The baseline pain was chiefly oppressive or burning with an intensity of 5.2 ± 1.4 on the verbal analogue scale. Exacerbations lasted 32.3 ± 26.1 minutes, were of a predominantly stabbing nature with an intensity of 8.3 ± 1.4, and in 69.4% of cases were accompanied by autonomic symptoms. Altogether 16.7% of the patients did not tolerate indomethacin beyond an indotest and 50% did so with side effects. In 13 cases at least one anaesthetic blockade was performed in the supraorbital or the greater occipital nerve or a trochlear injection of corticoids was carried out with a full response in 53.8% and a partial response in 38.5%.

Conclusions: Hemicrania continua is not an infrequent diagnosis in a headache clinic and, because it is a treatable condition, further knowledge on the subject is needed. Anaesthetic blockades of the supraorbital or greater occipital nerves or a trochlear injection of corticoids are the therapeutic options that must be taken into consideration when indomethacin is not well tolerated.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Age of Onset
  • Aged
  • Anesthetics, Local
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Bupivacaine
  • Chronic Disease
  • Female
  • Humans
  • Indomethacin / adverse effects
  • Indomethacin / therapeutic use
  • Injections
  • Magnetic Resonance Imaging
  • Male
  • Mepivacaine
  • Middle Aged
  • Migraine Disorders / drug therapy*
  • Migraine Disorders / epidemiology
  • Nerve Block
  • Ophthalmic Nerve
  • Symptom Assessment
  • Triamcinolone / administration & dosage
  • Triamcinolone / therapeutic use
  • Trochlear Nerve
  • Young Adult

Substances

  • Anesthetics, Local
  • Anti-Inflammatory Agents, Non-Steroidal
  • Triamcinolone
  • Mepivacaine
  • Indomethacin
  • Bupivacaine