Umpolung of fluoroform by C-F bond activation: direct difluoromethylation of lithium enolates

Angew Chem Int Ed Engl. 2012 Sep 17;51(38):9535-8. doi: 10.1002/anie.201203588. Epub 2012 Aug 29.

Authors

Toshiaki Iida¹, Ryota Hashimoto, Kohsuke Aikawa, Shigekazu Ito, Koichi Mikami

Affiliation

¹ Department of Applied Chemistry, Tokyo Institute of Technology, Tokyo 152-8552, Japan.

PMID: 22930536
DOI: 10.1002/anie.201203588

No abstract available

MeSH terms

Hydrocarbons, Fluorinated / chemical synthesis*
Hydrocarbons, Fluorinated / chemistry
Ketones / chemistry*
Lithium / chemistry*
Methylation
Molecular Structure
Organometallic Compounds / chemistry*
Quantum Theory

Substances

Hydrocarbons, Fluorinated
Ketones
Organometallic Compounds
Lithium