Diffuse gliomas in an adolescent with multiple enchondromatosis (Ollier's disease)

Oncol Lett. 2010 Jul;1(4):595-597. doi: 10.3892/ol_00000105. Epub 2010 Jul 1.

Abstract

Ollier's disease is characterized by the hamartomatous proliferation of cartilage cells, producing masses termed chondromas. A patient presented with Ollier's disease which was found to be associated with diffuse gliomas. Investigating this disease is crucial as there is a high risk of sarcomatous transformation of the skeletal lesions as well as an increased risk of developing extra-osseous malignancies.