Smile designing for edentulous patients has not been much investigated; the selection of artificial teeth is a task that follows multiple consequential steps such as choosing their form, size, material, color and disposition. Even if smile designing is thought to involve some artistic abilities, specific techniques or suggestions have been proposed in the literature to perform each step of the selection of artificial teeth, keeping in mind the importance of consultation and understanding of the patient preferences. This article will focus on the recovering of maxillary anterior teeth harmony in an edentulous patient; a clinical case report will show the rationale process of anterior teeth selection, supported by scientific guidelines found in the literature.