Challenges of genetic counseling in patients with autosomal dominant diseases, such as the hyper-IgE syndrome (STAT3-HIES)

J Allergy Clin Immunol. 2012 Dec;130(6):1426-8. doi: 10.1016/j.jaci.2012.07.030. Epub 2012 Sep 13.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cells, Cultured
  • Child
  • Child, Preschool
  • DNA Mutational Analysis
  • Female
  • Genes, Dominant
  • Genetic Counseling*
  • Humans
  • Immunoglobulin E / immunology*
  • Infant
  • Job Syndrome / diagnosis
  • Job Syndrome / genetics*
  • Male
  • Mutation / genetics*
  • Pedigree
  • STAT3 Transcription Factor / genetics*
  • Th17 Cells / immunology

Substances

  • STAT3 Transcription Factor
  • Immunoglobulin E