Long-term outcomes of one-stage anterior debridement, bone grafting, and internal fixation for the treatment of lower cervical tuberculosis with kyphosis

Br J Neurosurg. 2013 Apr;27(2):160-6. doi: 10.3109/02688697.2012.722706. Epub 2012 Sep 17.

Abstract

Background: Patients with spinal deformities and nerve compression due to spinal tuberculosis often require surgical intervention. The objective of this study was to assess the long-term therapeutic effectiveness of one-stage anterior debridement, bone grafting, and internal fixation for lower cervical tuberculosis with kyphosis.

Methods: Twenty-one patients with lower cervical tuberculosis and cervical kyphosis received one-stage anterior debridement, autologous iliac bone grafting, and internal plate fixation. Patients were followed-up postoperatively for at least 5 years. Outcome measures included neck pain using Visual Analogue Scale (VAS) scores, Frankel classification of spinal cord injury, and Cobb angle of cervical kyphosis.

Results: Eighteen patients had lesions in 2 vertebrae and 3 had lesions in 3 vertebrae. Cervical tuberculosis was cured in all patients. The mean preoperative VAS score for neck pain was 8 (range: 6-10), whereas the mean best postoperative VAS score was 0.6 (range: 0-3). Mean final VAS score was significantly higher than the best VAS score (2.14 vs. 0.62). Of the 13 patients with symptoms of spinal cord compression, 9 improved by 1 grade and 4 improved by 2 grades according to Frankel classification at final follow-up. The mean preoperative Cobb angle of cervical kyphosis was 29° (range: 15°-50°), whereas the mean postoperative Cobb angle at final follow-up was -1.8° (range: 2-7°).

Conclusions: One-stage anterior debridement, bone grafting, and internal fixation can effectively remove lesions, decompress the nerve, reduce pain, and correct kyphosis in patients with cervical tuberculosis and associated kyphosis. Long-term postoperative outcomes were satisfactory.

MeSH terms

  • Adult
  • Bone Plates*
  • Bone Transplantation / methods*
  • Cervical Vertebrae*
  • Debridement / methods*
  • Female
  • Humans
  • Ilium / transplantation
  • Kyphosis / surgery*
  • Male
  • Middle Aged
  • Neck Pain / surgery
  • Nerve Compression Syndromes / surgery
  • Pain Measurement
  • Postoperative Care / methods
  • Prospective Studies
  • Spinal Fusion / methods
  • Treatment Outcome
  • Tuberculosis, Spinal / surgery*
  • Young Adult