Complete radiologic response and long-term survival with use of systemic high-dose methotrexate for breast cancer-associated leptomeningeal disease

Clin Breast Cancer. 2012 Dec;12(6):445-9. doi: 10.1016/j.clbc.2012.07.010. Epub 2012 Sep 24.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Antimetabolites, Antineoplastic / administration & dosage
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / pathology
  • Carcinoma, Lobular / diagnostic imaging
  • Carcinoma, Lobular / drug therapy*
  • Carcinoma, Lobular / pathology
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Infusions, Intravenous
  • Magnetic Resonance Imaging
  • Meningeal Neoplasms / diagnostic imaging
  • Meningeal Neoplasms / drug therapy*
  • Meningeal Neoplasms / secondary
  • Methotrexate / administration & dosage*
  • Middle Aged
  • Radiography
  • Remission Induction / methods
  • Survivors*

Substances

  • Antimetabolites, Antineoplastic
  • Methotrexate