Sequencing the sixth base (5-hydroxymethylcytosine): selective DNA oxidation enables base-pair resolution

Angew Chem Int Ed Engl. 2012 Oct 22;51(43):10704-7. doi: 10.1002/anie.201204768. Epub 2012 Sep 26.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 5-Methylcytosine / analogs & derivatives
  • Base Pairing
  • Cytosine / analogs & derivatives*
  • Cytosine / chemistry
  • DNA / chemistry*
  • Deamination
  • Oxidation-Reduction
  • Sequence Analysis, DNA
  • Sulfites / chemistry

Substances

  • Sulfites
  • 5-hydroxymethylcytosine
  • 5-Methylcytosine
  • Cytosine
  • DNA
  • hydrogen sulfite