Isolated inferior sagittal sinus thrombosis caused by a rare combination of elevated lipoprotein (a) and iron deficiency anemia

Neurosciences (Riyadh). 2012 Oct;17(4):374-7.

Abstract

A 21-year-old woman was admitted with right hemiparesis, bilateral papilledema, negative myoclonus of right upper extremity, and bilateral pyramidal findings. An MRI showed no venous flow in the inferior sagittal sinus. Lipoprotein a (Lp [a]) level was high and iron deficiency anemia (IDA) was found. The coexistence of IDA and Lp (a) in patients with cerebral venous thrombosis is a very rare condition in adult patients. These risk factors should be investigated in patients with cerebral venous thrombosis.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Iron-Deficiency / complications*
  • Anemia, Iron-Deficiency / genetics
  • Corpus Callosum / pathology
  • Female
  • Humans
  • Hyperlipoproteinemias / complications*
  • Hyperlipoproteinemias / genetics
  • Imaging, Three-Dimensional
  • Magnetic Resonance Angiography
  • Magnetic Resonance Imaging
  • Methylenetetrahydrofolate Reductase (NADPH2) / genetics
  • Sagittal Sinus Thrombosis / diagnosis
  • Sagittal Sinus Thrombosis / etiology*
  • Sagittal Sinus Thrombosis / genetics
  • Young Adult

Substances

  • MTHFR protein, human
  • Methylenetetrahydrofolate Reductase (NADPH2)