Chromosomal tet(O)-harboring regions in Campylobacter coli isolates from turkeys and swine

Appl Environ Microbiol. 2012 Dec;78(23):8488-91. doi: 10.1128/AEM.02258-12. Epub 2012 Sep 28.

Abstract

In turkey-derived Campylobacter coli isolates of a unique lineage (cluster II), the tetracycline resistance determinant tet(O) was chromosomal and was part of a gene cassette (transposon) interrupting a Campylobacter jejuni-associated putative citrate transporter gene. In contrast, the swine-derived C. coli strain 6461 harbored a chromosomal tet(O) in a different genomic location.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Campylobacter Infections / microbiology
  • Campylobacter Infections / veterinary*
  • Campylobacter coli / drug effects*
  • Campylobacter coli / genetics*
  • Campylobacter coli / isolation & purification
  • Carrier Proteins / genetics
  • Chromosomes, Bacterial
  • DNA Transposable Elements
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics*
  • Genes, Bacterial
  • Molecular Sequence Data
  • Mutagenesis, Insertional
  • Poultry Diseases / microbiology*
  • Sequence Analysis, DNA
  • Swine
  • Swine Diseases / microbiology*
  • Tetracycline Resistance*
  • Turkeys

Substances

  • Carrier Proteins
  • DNA Transposable Elements
  • DNA, Bacterial
  • citrate-binding transport protein

Associated data

  • GENBANK/JQ613155
  • GENBANK/JQ613156