Orchidectomy alone for stage I seminoma of the testis

Cancer. 1990 Mar 1;65(5):1115-8. doi: 10.1002/1097-0142(19900301)65:5<1115::aid-cncr2820650513>3.0.co;2-6.

Abstract

Between 1983 and 1988, 113 patients with Stage I seminoma were managed after orchidectomy by surveillance rather than adjuvant radiotherapy. The actuarial risk of relapse at 3 years was 15.8% (95% confidence interval, 7.8% to 23.8%). All 13 patients who experienced a relapse are currently in remission (4 to 45 months after salvage therapy), although 5 suffered second relapses requiring further treatment. Close surveillance is a safe alternative to adjuvant radiotherapy in Stage I seminoma. However, the policy requires prolonged observation of patients with intensive use of resources. Therefore, adjuvant radiotherapy should be considered the treatment of choice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Combined Modality Therapy
  • Dysgerminoma / pathology
  • Dysgerminoma / surgery*
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Orchiectomy*
  • Recurrence
  • Remission Induction
  • Reoperation
  • Testicular Neoplasms / pathology
  • Testicular Neoplasms / surgery*